Is Vaping Giving You Popcorn Lung? Is it True That Vaping Can Cause Popcorn Lung? Freeman Vape Health experts are sounding the alarm about a serious condition linked to vaping, known as "popcorn lung" or bronchiolitis obliterans. This irreversible lung disease is caused by harmful chemicals, like diacetyl, found Popcorn Lung vs. Lung Cancer: Understanding the Critical Differences (and Why It Matters)